产品货号：
Z22930
中文名称：
PAK3抗体
英文名称：
Anti-PAK3 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PAK3 Antibody |
| 指标别名 | PAK3;OPHN3;Serine/threonine-protein kinase PAK 3;EC 2.7.11.1;Beta-PAK;Oligophrenin-3;p21-activated kinase 3;PAK-3 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,FCM,ELISA |
| 基因名称 | PAK3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human PAK3 recombinant protein (Position:M1-D263). |
| 实际分子量 | 62KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Serine/threonine-protein kinase PAK 3?is an?enzyme?that in humans is encoded by the?PAK3?gene.PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling.PAK proteins,a family of serine/threonine p21-activating kinases,serve as targets for the small GTP binding proteins Cdc42 and RAC and have been implicated in a wide range of biological activities.The protein encoded by this gene forms an activated complex with GTP-bound RAS-like (P21),CDC2 and RAC1 proteins which then catalyzes a variety of targets.This protein may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity.Defects in this gene are the cause of non-syndromic mental retardation X-linked type 30 (MRX30),also called X-linked mental retardation type 47 (MRX47).Alternatively spliced transcript variants encoding different isoforms have been identified. |
| Uniprot ID | O75914 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | p21 (RAC1) activated kinase 3 |
| 蛋白名全称 | Serine/threonine-protein kinase PAK 3 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells Enzyme linked immunosorbent assay (ELISA) 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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